Innovating for Health: The Science Behind Our Cannabis Salves

The Lab

At Main Street Health (MSH), we are committed to advancing the science of medical cannabis to provide Ohio’s patients and consumers with safe, effective, and innovative therapeutic options. One of our standout products is our transdermal gel, sometimes referred to as a salve. This product leverages cutting-edge nanoencapsulation technology to enhance the delivery and efficacy of cannabinoids through the skin.

Understanding Nanoencapsulation in Cannabis Salves

Cannabinoids, the active compounds in cannabis, are inherently lipophilic, meaning they dissolve in fats but not in water. This characteristic poses a challenge for topical applications, as the skin’s outer layer is designed to repel water-soluble substances, limiting the penetration of fat-soluble molecules like cannabinoids.

To overcome this barrier, MSH employs nanoencapsulation technology. This process involves enclosing cannabinoids within microscopic lipid-based carriers, effectively transforming them into a more water-compatible form. These nano-sized carriers can traverse the skin’s protective layers more efficiently, delivering cannabinoids into the bloodstream and enabling both localized and systemic therapeutic effects.

Benefits of Nanoencapsulated Transdermal Gels

  1. Enhanced Bioavailability: Nanoencapsulation increases the solubility of cannabinoids, facilitating better absorption through the skin and into systemic circulation.
  2. Targeted Delivery: The technology allows for precise delivery of cannabinoids to specific areas, providing localized relief while minimizing potential side effects.
  3. Controlled Release: Nanoencapsulated formulations, when combined with the right delivery devices, can offer sustained release of cannabinoids, ensuring prolonged therapeutic effects and reducing the need for frequent application.

Scientific Validation

Recent studies have highlighted the efficacy of nanoencapsulated cannabinoids in transdermal applications. Research published in the journal Pharmaceutics indicates that transdermal delivery systems can effectively transport cannabinoids through the skin, offering a non-invasive alternative for systemic administration.  Additionally, a pilot clinical study demonstrated that topical nanoencapsulated cannabidiol cream could protect against UV-A–induced DNA damage, showcasing the potential of such formulations in dermatological applications.

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MSH’s Commitment to Quality and Community

Operating from our facility in Dayton, Ohio, MSH is dedicated to producing high-quality, consistent, and safe cannabis-based products. Our proprietary ethanol-based extraction process ensures the purity of our extracts, which we use to create a diverse range of products, including our transdermal gels.Our solventless extractions provide even more range, variety, and choice for our customers.

Beyond our scientific endeavors, we take pride in being an active and positive member of the Dayton community. Our partnerships and local initiatives reflect our commitment to supporting and enriching the lives of Ohio residents.

Explore Our Products

We invite Ohio residents to experience the benefits of our innovative cannabis salves and other products. To find a dispensary near you that carries MSH products, please visit our Where to Buy page. Discover how our science-driven approach to cannabis can contribute to your health and well-being.

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